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Pharmaceutical Manufacturing Equipment – Business Overview
1. Solid-Dosage Equipment
• Milling: particle-size reduction of APIs
• Sieving & classification: consistent granule size
• Granulators: wet or dry granulation for tablets/capsules
• Dryers: ovens, fluid-bed dryers – moisture removal for stability
• Tablet presses: compression of powders into tablets
• Capsule fillers: powder/granule filling into hard/soft capsules
• Coaters: film, sugar, or enteric coating for taste-masking or controlled release
• Packaging lines: bottle, blister, sachet, stick-pack, cartoning, labeling, case-pack, serialization, printing
2. Liquid-Dosage Equipment
• Mixing & dissolving tanks for API and excipients
• Bottle washers – glass vial cleaning for sterile liquids
• BFS (blow-fill-seal) machines – aseptic filling and sealing
• Sterilizers – terminal sterilization of finished liquids
• End-of-line packaging (bottling, labeling, cartoning, serialization)
3. Sterile-Dosage Equipment
• Membrane & cartridge filtration – microbial and particulate removal
• Purification systems – HPLC/GC for in-process control
• Autoclaves / SIP systems – validated sterilization
• Pre-filled syringe/fill-finish isolators – aseptic filling & stoppering
• Freeze-dryers (lyophilizers) – conversion of liquids to sterile powders
• Secondary packaging lines (same formats as above)
4. Biologics Equipment
• Synthesis reactors – raw-material preparation
• Fermenters/bioreactors – microbial or mammalian cell culture
• High-speed centrifuges – cell harvest & clarification
• Lyophilizers – sterile bulk or vial freeze-drying
• Final packaging lines (bottle, blister, sachet, cartoning, labeling, serialization)
5. API (Active Pharmaceutical Ingredient) Equipment
• Reactors, towers, kettles, pumps & tanks – chemical synthesis
• Crystallizers – controlled crystal formation
• Filter presses – solid-liquid separation post-crystallization
• Dryers – vacuum or conical dryers for API stability
• Vacuum systems – process-specific vacuum supply
• Chiller loops – precise temperature control
• Liquid fillers & solid packers – bulk API packaging
6. Traditional Chinese Medicine (TCM) Equipment
• Extractors – solvent or water extraction of botanical actives
• Blending vessels – uniform mixing of herbal extracts
• Pill/pellet machines – TCM pill forming
• Spray dryers – liquid-to-powder conversion
• Vacuum dryers – low-temperature drying of heat-sensitive TCM products
• Final packaging lines (bottle, blister, sachet, cartoning, labeling, serialization)
7. Utility & Ancillary Equipment
• Chillers, air compressors, vacuum pumps – utilities for process support
• HVAC & clean-room systems – temperature, humidity, particulate control
• Dust collectors – airborne-particle containment
• PSA nitrogen generators – inert-gas supply
• Boilers – steam or hot-water generation
• Piping, valves, instrumentation – fluid conveyance, control and monitoring
8. Infrastructure & Support Facilities
• Manufacturing buildings, QC labs, animal houses, warehouses, cold rooms, hazardous-material stores
• Fire-pump stations – life-safety compliance
• Electrical substations – reliable power supply
• Wastewater-treatment plants – effluent compliance